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Dr RC Mishra » Organic, Medicinal & Pharmaceutical Chemist

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Research

Publications, Patents, Book Chapters

Complete Curriculum-Vitae

Currently I am working towards optimization of anticancer activity of recently discovered tubulin interactive compound Noscapine and its derivatives.

 

de: Struktur von Narkotin (Noscapin); en: Stru...

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My current project involves the design and synthesis of novel analogs of Noscapine. Moreover, I am also preparing conjugates of known cancer drugs like Docetaxel and Doxorubicin and potent Noscapine analogs with Peptides and Biomolecules which are over expressed in different kind of tumor cells using Cleavable Linkers. Apart from this I have also conjugated a derivative of Noscapine with NIR dyes which have selective binding affinity with tumor cells. The work from the current project has resulted in the preparation of a number of manuscripts and patent application.

I have expertise in the design and synthesis of Nucleosides (natural, unnatural and fluorescent) Nucleotides, Carbohydrates, Heterocycles and Natural products. I use various spectroscopic techniques (NMR, MS, IR, UV etc.) to characterize the novel molecules.

In my Doctoral Research, most of the work was related to synthesis of Glycoconjugates, C-Nucleosides and Unnatural nucleosides. I also have hands-on experience in combinatorial synthesis and automated small molecule synthesizer.

In my research career till date I have published 20 papers in international journals and applied for 5 Indian and 1 US patent (in process).

My Research Interests include, Cancer Biology, Drug Design, Targeted Drug Delivery (Receptor and Nanoparticle assisted) and Biological Imaging. I do also have high enthusiasm to design and develop novel small molecules having Carbohydrate, Nucleoside or Natural product skeleton for therapeutic purpose.

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Incoming terms:

Permanent link to this article: http://www.rcmishra.com/

PhD Thesis

Doctorate Incoming terms:phd thesis in drug discoveryphd thesis on anticancer

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23 comments

  1. Arvind Mishra

    Your current work on cancer biology looks very promising in context to alleviate human sufferings from the dreaded disease.Please keep it up!

  2. Nige R Nigga

    great research!

  3. Nige R Nigga

    Why did you delete my comment?
    I really think this is great research! 

  4. Tumor rupture

    Cancer found in the cells with the busts is breast cancers. So thousands of breast tissue which is developing in the abnormal along with out of control means can be a dangerous cancer.

  5. Diq N Mahazz

    You must contiune research such as this Dr, you help so many people with these research!

  6. Rafik landge

    There is some problem in my leg i need your help and i need your number
    please do the needful for me as soon as possible 

    1. Muttaquee HUSAIN

      i have been searching the medecines for last two months and could not find anywhere in calcutta, benares delhi or pune. where can i get this?

  7. k.c.sahoo

    Sir, I am in problem & your medicines so great worked for leg pain for old age people. My mom also suffer in this pain but your medicines are great & amazed work. But i didn’t get your medicines properly so please give me your perfect address of medicines stores in Orissa.

    Thanks
    K C Sahoo 09337855749

  8. prashant kadam

    hello , this is prashant kadam friom mumbai . we get to know about your effective medicine on joint pain from one of our relativ . but they dont have your contact info . they just gave me one small card which was bellonging to ur medicine packe . it is small yellor color card with text “Asali bay ki dava” and ur name Dr R C Mishra reg no :35344 ,Can I get contact no of mumbai office? . my mother has problem in her leg joint, she is suffering from last 5-6 years .. please reply with ur contact no so that i can contact you … , thank you veru much ..

    1. rekha kulkarni

      i am taking your medicin GM asali bye ki dava i got much relife so please give me mumbai address or address from where i can call for medicine

  9. ramchandra yadav

    my wife and other relative in bay diesecies and your medicine is perfect for this diciedese bhagwan dhanwantari ke avtar ho ramchandra yadav bhilai

  10. regrowth

    Thanks for sharing extremely good informations. Your web-site is
    really cool. I’m impressed by the details that you simply have on this web site. It shows how nicely someone perceives this subject. Bookmarked this web site, will keep coming back for extra articles. You, my pal, ROCK!

  11. HUSAIN

    Dear Sir, Dear Dr Mishra,
    I would like to order / purchase the tablets and capsules of your “GM Asli Bay Ki Dawa” Gathiya Bay va Jodon ke dard ki uttam Dawa”
    How and where can I have it?
    I will be going to India in February next and will be staying in Kolkata, Delhi, Jaipur, Mumbai and in Pune.
    Can you send me any addresses in one of these cities and confirm that I will get the original, authentic medecine form one of thoses adresses?
    Three of my friends having the problems of joints and articulation and one of them has tried it and gor so much relief within three days ( two years back) that he wants it once again and also give it to his friends.
    Thanks so much for your help
    waiting for your earliest reply at your convenience
    with cordial regards
    Muttaquee HUSAIN

  12. HUSAIN

    how can I contact you or your outlets for the medecines?

    1. HUSAIN

      how can I contact you or your outlets to get medecines?

  13. nirmal gill

    Dear Dr Mishra,
    I would like to order / purchase the tablets and capsules of your “GM Asli Bay Ki Dawa” Gathiya Bay va Jodon ke dard ki uttam Dawa”
    How and where can I have it? is there any dealer in punjab.

    1. nirmal gill

      Dear Dr Mishra,
      I would like to order / purchase the tablets and capsules of your “GM Asli Bay Ki Dawa” Gathiya Bay va Jodon ke dard ki uttam Dawa”
      How and where can I have it? is any dealer of your medicines in punjab?

  14. Rasaq Adisa

    Pls Dr, I would like to have list of impact factor journal PDF list for Communication/Journalism through my mail. Thanks.

  15. saleem ali

    Sir, I am in problem & your medicines so great worked for leg pain for old age people. My mom also suffer in this pain but your medicines are great & amazed work. But i didn’t get your medicines properly so please give me your perfect address of medicines stores in haryana(india)

  16. saleem ali

    Sir, I am in problem & your medicines so great worked for leg pain for old age people. My mom also suffer in this pain but your medicines are great & amazed work. But i didn’t get your medicines properly so please give me your perfect address of medicines stores in Orissa.

    Thanks
    saleem ali 9996884038

  17. Uge Kak

    I have a problem with my foot, i belive it may be cancerous? How can i find this out?

    1. Dr RC Mishra

      Please visit a hospital and consult a Doctor for Cancer related diagnostics.

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