Publications, Patents, Book Chapters
Currently I am working towards optimization of anticancer activity of recently discovered tubulin interactive compound Noscapine and its derivatives.
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My current project involves the design and synthesis of novel analogs of Noscapine. Moreover, I am also preparing conjugates of known cancer drugs like Docetaxel and Doxorubicin and potent Noscapine analogs with Peptides and Biomolecules which are over expressed in different kind of tumor cells using Cleavable Linkers. Apart from this I have also conjugated a derivative of Noscapine with NIR dyes which have selective binding affinity with tumor cells. The work from the current project has resulted in the preparation of a number of manuscripts and patent application.
I have expertise in the design and synthesis of Nucleosides (natural, unnatural and fluorescent) Nucleotides, Carbohydrates, Heterocycles and Natural products. I use various spectroscopic techniques (NMR, MS, IR, UV etc.) to characterize the novel molecules.
In my Doctoral Research, most of the work was related to synthesis of Glycoconjugates, C-Nucleosides and Unnatural nucleosides. I also have hands-on experience in combinatorial synthesis and automated small molecule synthesizer.
In my research career till date I have published 20 papers in international journals and applied for 5 Indian and 1 US patent (in process).
My Research Interests include, Cancer Biology, Drug Design, Targeted Drug Delivery (Receptor and Nanoparticle assisted) and Biological Imaging. I do also have high enthusiasm to design and develop novel small molecules having Carbohydrate, Nucleoside or Natural product skeleton for therapeutic purpose.
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23 comments
Arvind Mishra
April 16, 2011 at 07:20 (UTC -4)
Your current work on cancer biology looks very promising in context to alleviate human sufferings from the dreaded disease.Please keep it up!
Nige R Nigga
October 22, 2011 at 20:10 (UTC -4)
great research!
Nige R Nigga
October 24, 2011 at 17:13 (UTC -4)
Why did you delete my comment?
I really think this is great research!
Tumor rupture
January 30, 2012 at 16:53 (UTC -4)
Cancer found in the cells with the busts is breast cancers. So thousands of breast tissue which is developing in the abnormal along with out of control means can be a dangerous cancer.
Diq N Mahazz
February 21, 2012 at 17:18 (UTC -4)
You must contiune research such as this Dr, you help so many people with these research!
Rafik landge
September 6, 2012 at 10:27 (UTC -4)
There is some problem in my leg i need your help and i need your number
please do the needful for me as soon as possible
Muttaquee HUSAIN
March 23, 2013 at 13:03 (UTC -4)
i have been searching the medecines for last two months and could not find anywhere in calcutta, benares delhi or pune. where can i get this?
k.c.sahoo
September 8, 2012 at 03:00 (UTC -4)
Sir, I am in problem & your medicines so great worked for leg pain for old age people. My mom also suffer in this pain but your medicines are great & amazed work. But i didn’t get your medicines properly so please give me your perfect address of medicines stores in Orissa.
Thanks
K C Sahoo 09337855749
prashant kadam
November 27, 2012 at 23:38 (UTC -4)
hello , this is prashant kadam friom mumbai . we get to know about your effective medicine on joint pain from one of our relativ . but they dont have your contact info . they just gave me one small card which was bellonging to ur medicine packe . it is small yellor color card with text “Asali bay ki dava” and ur name Dr R C Mishra reg no :35344 ,Can I get contact no of mumbai office? . my mother has problem in her leg joint, she is suffering from last 5-6 years .. please reply with ur contact no so that i can contact you … , thank you veru much ..
rekha kulkarni
April 20, 2013 at 08:20 (UTC -4)
i am taking your medicin GM asali bye ki dava i got much relife so please give me mumbai address or address from where i can call for medicine
ramchandra yadav
December 14, 2012 at 07:18 (UTC -4)
my wife and other relative in bay diesecies and your medicine is perfect for this diciedese bhagwan dhanwantari ke avtar ho ramchandra yadav bhilai
regrowth
December 15, 2012 at 14:36 (UTC -4)
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HUSAIN
January 18, 2013 at 17:21 (UTC -4)
Dear Sir, Dear Dr Mishra,
I would like to order / purchase the tablets and capsules of your “GM Asli Bay Ki Dawa” Gathiya Bay va Jodon ke dard ki uttam Dawa”
How and where can I have it?
I will be going to India in February next and will be staying in Kolkata, Delhi, Jaipur, Mumbai and in Pune.
Can you send me any addresses in one of these cities and confirm that I will get the original, authentic medecine form one of thoses adresses?
Three of my friends having the problems of joints and articulation and one of them has tried it and gor so much relief within three days ( two years back) that he wants it once again and also give it to his friends.
Thanks so much for your help
waiting for your earliest reply at your convenience
with cordial regards
Muttaquee HUSAIN
HUSAIN
January 19, 2013 at 09:20 (UTC -4)
how can I contact you or your outlets for the medecines?
HUSAIN
January 19, 2013 at 09:21 (UTC -4)
how can I contact you or your outlets to get medecines?
nirmal gill
February 8, 2013 at 10:58 (UTC -4)
Dear Dr Mishra,
I would like to order / purchase the tablets and capsules of your “GM Asli Bay Ki Dawa” Gathiya Bay va Jodon ke dard ki uttam Dawa”
How and where can I have it? is there any dealer in punjab.
nirmal gill
February 8, 2013 at 11:00 (UTC -4)
Dear Dr Mishra,
I would like to order / purchase the tablets and capsules of your “GM Asli Bay Ki Dawa” Gathiya Bay va Jodon ke dard ki uttam Dawa”
How and where can I have it? is any dealer of your medicines in punjab?
Rasaq Adisa
March 6, 2013 at 19:17 (UTC -4)
Pls Dr, I would like to have list of impact factor journal PDF list for Communication/Journalism through my mail. Thanks.
mandeep
April 6, 2013 at 10:04 (UTC -4)
sir pls mail me ur contact no at [email protected]
saleem ali
April 24, 2013 at 04:23 (UTC -4)
Sir, I am in problem & your medicines so great worked for leg pain for old age people. My mom also suffer in this pain but your medicines are great & amazed work. But i didn’t get your medicines properly so please give me your perfect address of medicines stores in haryana(india)
saleem ali
April 24, 2013 at 04:25 (UTC -4)
Sir, I am in problem & your medicines so great worked for leg pain for old age people. My mom also suffer in this pain but your medicines are great & amazed work. But i didn’t get your medicines properly so please give me your perfect address of medicines stores in Orissa.
Thanks
saleem ali 9996884038
Uge Kak
April 30, 2013 at 23:55 (UTC -4)
I have a problem with my foot, i belive it may be cancerous? How can i find this out?
Dr RC Mishra
April 30, 2013 at 23:58 (UTC -4)
Please visit a hospital and consult a Doctor for Cancer related diagnostics.