HiStory of Carbocyclic Nucleosides

Carbocyclic Nucleosides is the name given to the class of molecules which are very similar to Nucleosides despite the fact that their furanose ring system in sugar counterpart is replace by a cyclopentyl ring. The first molecule, classified as Carbocyclic Nucleoside was Synthesized in a lab of Southern Research Institute in Birmingham, Albama. It was the carbocyclic analog of adenosine, then known as CAdenosine.

 Aristeromycin

In following years, reports of isolation  and characterization of a bioactive ingredient  from Streptomyces citricolor were published and the compound having antibiotic property was subsequently named as Aristeromycin.

 

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