HiStory of Carbocyclic Nucleosides
Carbocyclic Nucleosides is the name given to the class of molecules which are very similar to Nucleosides despite the fact that their furanose ring system in sugar counterpart is replace by a cyclopentyl ring. The first molecule, classified as Carbocyclic Nucleoside was Synthesized in a lab of Southern Research Institute in Birmingham, Albama. It was the carbocyclic analog of adenosine, then known as C–Adenosine.
In following years, reports of isolation and characterization of a bioactive ingredient from Streptomyces citricolor were published and the compound having antibiotic property was subsequently named as Aristeromycin.