Design & Development of Unnatural Nucleosides as Antiviral & Anti-Cancer Agents

Design & Development of Unnatural Nucleosides as Antiviral & Anti-Cancer Agents   Ram C. Mishra   College of Pharmacy, University of Georgia, GA 30602, USA ¬†Unnatural nucleosides are the variants (chemically modified analogs) of five natural nucleosides which constitute the structure of DNA and RNA. Since the first preparation and later, the isolation of unnatural nucleosides from plants; nucleoside chemistry […]

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Bosutinib – Bosulif approved for Leukemia by Pfizer

A new anticancer drug for Leukemia has been approved by FDA. The drug treats chronic myelogenous leukemia (CML), a blood and bone marrow disease that usually affects seniors.   It works by inhibiting the enzyme Tyrosine Kinase.   Incoming terms:Bosulif

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Anticancer targets amenable by nucleoside drugs

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Anticancer chemotherapy using targets amenable by nucleoside drugs: There are some recently discovered targets where compounds of ‘nucleoside’ class or just the ‘Nucleosides’ have shown some interesting biological effects.¬† Most of these could be modulated to get novel nucleoside based highly targeted therapy of various cancer sub types.

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