Nucleoside-Prodrug Synthesis: Chiral & Non Chiral Reagents
Since the development of the Pro-drug strategy for the anti viral nucleosides for the treatment of HIV by Christopher McGuigan in 1993, there have been various attempts in designing a reagent for the chiral pro drug synthesis. Since the market debut of Gilead’s Blockbuster drug the reagent (shown as Chiral reagent in the graphics below) … Read more