Design & Development of Unnatural Nucleosides as Antiviral & Anti-Cancer Agents

Design & Development of Unnatural Nucleosides as Antiviral & Anti-Cancer Agents   Ram C. Mishra   College of Pharmacy, University of Georgia, GA 30602, USA  Unnatural nucleosides are the variants (chemically modified analogs) of five natural nucleosides which constitute the structure of DNA and RNA. Since the first preparation and later, the isolation of unnatural nucleosides from plants; nucleoside chemistry […]

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Bosutinib – Bosulif approved for Leukemia by Pfizer

A new anticancer drug for Leukemia has been approved by FDA. The drug treats chronic myelogenous leukemia (CML), a blood and bone marrow disease that usually affects seniors.   It works by inhibiting the enzyme Tyrosine Kinase.   Incoming terms:Bosulif

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CHEM MED CHEM Article: Adenosine A2A Receptor Antagonists: New 8-Substituted 9-Ethyladenines as Tools for in vivo Rat Models of Parkinson’s Disease

Adenosine A2A Receptor Antagonists: New 8-Substituted 9-Ethyladenines as Tools for in vivo Rat Models of Parkinson’s Disease Rosaria Volpini, Prof., Diego Dal Ben, Dr., Catia Lambertucci, Dr., Gabriella Marucci, Prof. Dr., Ram Chandra Mishra, Dr., Anna Teresa Ramadori, Dr., Karl-Norbert Klotz, Prof., Maria Letizia Trincavelli, Dr. , Claudia Martini, Prof., Gloria Cristalli, Prof. Abstract: A new series of 8-substituted 9-ethyladenine derivatives has been synthesized and […]

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