Design & Development of Unnatural Nucleosides as Antiviral & Anti-Cancer Agents

Design & Development of Unnatural Nucleosides as Antiviral & Anti-Cancer Agents   Ram C. Mishra   College of Pharmacy, University of Georgia, GA 30602, USA ¬†Unnatural nucleosides are the variants (chemically modified analogs) of five natural nucleosides which constitute the structure of DNA and RNA. Since the first preparation and later, the isolation of unnatural nucleosides from plants; nucleoside chemistry […]

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Truvada: Recommended for pre-exposure prophylaxis (PrEP)

The United States FDA‘s advisory committee has recommended that Truvada should be approved for HIV prophylaxis. Gilead Sciences Inc is the manufacturer of the drug to be used in combination therapy of AIDS. The drug is a RTI (Reverse Transcriptase Inhibitor), although it can not destroy the virus but stops their replication. Truvada consists of Emtricitabine and Tenofovir Disoproxil Fumarate […]

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