Anticancer targets amenable by nucleoside drugs

Anticancer chemotherapy using targets amenable by nucleoside drugs: There are some recently discovered targets where compounds of ‘nucleoside’ class or just the ‘Nucleosides’ have shown some interesting biological effects.  Most of these could be modulated to get novel nucleoside based highly targeted therapy of various cancer sub types.

HiStory of Carbocyclic Nucleosides

Carbocyclic Nucleosides is the name given to the class of molecules which are very similar to Nucleosides despite the fact that their furanose ring system in sugar counterpart is replace by a cyclopentyl ring. The first molecule, classified as Carbocyclic Nucleoside was Synthesized in a lab of Southern Research Institute in Birmingham, Albama. It was … Read more

Influenza Viruses

Image via Wikipedia Influenza viruses are a group of RNA viruses from Orthomyxoviridae family. These are 3 in number namely: Influenzavirus A, Influenzavirus B and Influenzavirus C. Each of these genus has only one species namely influenza A virus, influenza B virus and influenza C virus. Among the three, type A causes severe disease and … Read more

Impact Factor 2011: Journal Citation Reports by Thomson Reutors

The impact factor report of Journals for the year 2011 is now available. The list is being embeded here as an excel file which can be downloaded and viewed on full screen by choosing the options below. 2012 Impact Factors are Available Here: Updated To Download the List as MS Excel File, Click below on Save … Read more

Truvada: Recommended for pre-exposure prophylaxis (PrEP)

The United States FDA‘s advisory committee has recommended that Truvada should be approved for HIV prophylaxis. Gilead Sciences Inc is the manufacturer of the drug to be used in combination therapy of AIDS. The drug is a RTI (Reverse Transcriptase Inhibitor), although it can not destroy the virus but stops their replication. Truvada consists of … Read more